Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence.
The pathology associated with malaria infection is largely due to the ability of infected human RBCs to adhere to a number of receptors on endothelial cells within tissues and organs.This phenomenon is driven by the export of parasite-encoded proteins to the host cell, the exact function of many of which is still unknown.Here we inactivate the func